KRT15 anticorps (CF®488A)
Aperçu rapide pour KRT15 anticorps (CF®488A) (ABIN7655957)
Antigène
Voir toutes KRT15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker)(KRT15/2957), CF488A conjugate
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Attributs du produit
- Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant full-length human KRT15 protein
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Isotype
- IgG2c, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: HCT116, HeLa, A431 cells. Skin or Colon.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- KRT15 (Keratin 15 (KRT15))
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Autre désignation
- Keratin 15
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Sujet
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Synonyms: CK15, Cytokeratin 15, K1CO, Ka15, Keratin 15 basic, Keratin 15 beta, Keratin complex 1 acidic gene 15, Keratin type I cytoskeletal 15, KRT15, KRTB, KRTL15, Type I cytoskeletal 15, Type I keratin Ka15
Gene Symbol: KRT15
Tissue Expression: Epidermal cells
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Poids moléculaire
- 52 kDa
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ID gène
- 3866
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UniProt
- P19012
Antigène
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